I have a 2001 Acura 3.2 CL Type S. Yesterday my car started to vibrate and my engine light went on. I went to the mechanic, and said it could be the sparkplugs. Then I went to autozone and got my engine scanned, and three codes came up. According to the code, cylinders 1,4,6 misfired. I replaced all six sparkplugs with new Iridium/Platnimun sparkplugs. However, I still have the same problem. My car vibrates and my engine light is on. I scanned it again, and the same codes came up. What else could be wrong? What should be my next step?

check the wires. make sure they go to the right plug, and make sure that they're completely shut. it's easy not to close them good they pop back off, causing that number cylinder to misfire, and it may have fouled another plug if driven long enough like that.